Closed-loop atomization reduces aerosol contamination caused by open system metering.
Open system pressurization can contaminate aerosols. Maintaining a closed circuit during mechanical ventilation is essential for safety and reduces patient bioaerosol risk. Nebulizer choice affects bioaerosol release; open system jets release more. Interruption of the ventilation circuit during jet nebulizer refill can release patient bioaerosols. Because the circuit remains intact, no particles are released during VMN medication refills.
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